Phenotypic Switching

<p>1. The fundamentals of phenotypic plasticity</p> <p>2. Rethinking the role of chance in the explanation of cell differentiation</p> <p>3. Random walk across the epigenetic landscape</p> <p>4. Maneuvering protein functions and functional levels by structural excursions</p> <p>5. Prion-mediated phenotypic diversity in fungi</p> <p>6. Bistability in virus - host interaction networks underlies the succes of hepatitis C treatments</p> <p>7. Quantifyinh Waddington landscapes, paths, and kinetics of cell fate decision making of differentiation/development</p> <p>8. The physics of cell fate</p> <p>9. Disentangling the environmentally induced and stochastic development components of phenotypic variation</p> <p>10. The evolution of cell differentiation in animals: biomolecular condensates as amplification hubs of inherent cell functions</p> <p>11. Phenotypic switching and its evolutionary consequences</p> <p>12. Cell-state organization by exploratory sloppy dynamics</p> <p>13. Emergence of metabolic heterogeneity in cell populations: lessons from budding yeast</p> <p>14. Stochastic phenotypic switching in endothelial cell heterogeneity</p> <p>15. Regulation of phenotypic plasticity from the perspective of evolutionary developmental biology</p> <p>16. Phenotypic plasticity and the origins of novelty</p> <p>17. Niche construction and the transition to herbivory: Phenotype switching and the organization of new nutritional modes</p> <p>18. NAture, nurture, and noise in bird song ontogeny as determinants of phenotypic and functional variation among dialects</p> <p>19. Domestication as a process generating phenotypic diversity</p> <p>20. The glycobiology of ovarian cnacer progression: phenotypic switches an microenvironmental influences</p> <p>21.Epithelia-mesenchymal transition in cancer</p> <p>22. Phenotypic switching and prostate diseases: a model proposing a causal link benign prostatic hyperplasia and prostate cancer</p> <p>23. Phenotypic plasticty and lineage switching in prostate cancer</p> <p>24. Implications of non-genetic heterogeneity in cancer drug resistance and malignant progression</p> <p>25. Phenotypic plasticity: the emergence of cancer stem cells and collective cell migration</p> <p>26. Adaptive phenotypic switching in breast cancer in response to matric deprivation</p> <p>27. Phenotypic instability induced by tissue disuption at the origin of cancer</p> <p>28. Evolutionary strategies to overcome cancer cell resistance ot treatment</p>